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Northcote; Poole, Peter and Joan, St. Top of pageAbstractThe peripheral blood lymphocytes of 36 adult patients with moderate to severe atopic dermatitis had reduced natural killer (NK) cell activity when measured against 51Crlabeled K 562 cells. The decrease in NK cells activity was not related to the serum IgE level, but was related to the severity of the skin disease. Addition of autologous monocytes of the assay reduced the NK cell activity and concealed the enhancing effect of interferon addition in a 4h assay. The NK cell activity of lymphocytes could be reduced in vitro by addition of prostaglandin E1, or increased by addition of interferon similar to lymphocytes from persons without atopic disease.Our present findings raise the possibility that the reduced NK cell activity may be secondary to the skin disease, and due to in vivo interaction between NK cells and monocytes, or to low numbers of NK cells in peripheral blood.Top of pageReferencesRajka, G: Atopic dermatitis. Major Problems in Dermatology 1975 3: Edited by A Rook, London, Saunders, pp 19 Juhlin, L, Johansson, SGO, Bennich, H, H C, Thyresson, N: Immunoglobulin E in dermatoses: level in atopic dermatitis and urticaria. Arch Dermatol 1969 100: 10 PubMed ThestrupPedersen, K, Ellegaard, J, Thulin, H, Zachariae, H: PPD and mitogen responsiveness of lymphocytes from patients with atopic dermatitis. Clin Exp Immunol 1977 27: 118 PubMed  ChemPort Jensen, JR, Cramers, M, ThestrupPedersen, K: Subpopulations of T lymphocytes and nonspecific suppressor cell activity in patients with atopic dermatitis. Clin Exp Immunol 1981 45: 118 PubMed  ChemPort Jensen, JR, ThestrupPedersen, K: Modulating effects of enzymes on T, and T cells in patients with atopic dermatitis. Free Porn Movies and Videos. The best porn resource for all your free porno needs. . 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